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Even though benzodiazepines and barbiturates can be detected by certain kinds of drug screening tests, detecting them does not mean the drugs are the cause of the person's symptoms.

Most hospital laboratories cannot measure the blood level of most sedatives.

People are usually hospitalized during the withdrawal process because a severe reaction is possible.If people who take a dangerous overdose of antianxiety drugs or sedatives have significant respiratory, heart, or blood pressure problems, they should be hospitalized in an area where they can be monitored (such as an intensive care unit).People with severe withdrawal symptoms usually need to be treated in a hospital, sometimes in an intensive care unit, and be closely monitored.Heavy sedation in critical care to facilitate endotracheal tube tolerance and ventilator synchronization, often with neuromuscular blocking agents, was routine until relatively recently.The modern ICU ventilator is equipped with a wide range of ventilatory modes and, with the addition of electronic flow triggering, synchronization problems have largely disappeared.

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