Her first breakthrough in show business came when she was made a teenage fashion model; she later took up acting as her career when her aunt, Carol Merrill, advised her to seek a career in that path.
Since becoming an actress in 1988 when she was cast in Who’s the Boss, Carla Gugino has featured in Californication, A Season of Hope, Entourage, Spin City, Man of Steel, Faster, Davis Rules, The Wonder Years, Justified, I Melt With You, Women in Trouble, Righteous, The Brink, American Gangster, Match and few other films and TV series.
Hooking up with one or two of your hallmates within the first few days of school, however, is a definite no-no.
As a new student, you’ll get a feel for student life and get exposed to every kind of guy—frat boys, athletes, pre-meds, business students and artsy guys, too.
It wasn't until the year 2001 though that she rose to prominence with her starring role as Ingrid Cortez in the "Spy Kids" film franchise; "Spy Kids", "Spy Kids 2: The Island of Lost Dreams", also "Spy Kids 3-D: Game Over".
She, moreover, was also known for her action in "Sin City", "Night at the Museum", "Race to Witch Mountain", "Sucker Punch", as well as "Man of Steel".
She, however, decided to leave New York for Los Angeles and began modeling and enrolling in an acting class there.
Kicking off her professional acting career in the late 1980s, Gugino early appearances were on TV features "Saved by the Bell", "Who's the Boss? D.", "The Wonder Years", and a recurring role on "Falcon Crest".